Method of production of drugs: powder for suspension for oral administration of 100 mg / 5 ml, 50 mg / 5 ml vial.; Table., Film-coated, 400 mg cap. (Except F.mortiferum and F.varium); also active against the M & E are resistant to penicillins, cephalosporins first generation, aminoglycosides, are resistant to the drug: streptococcus group D; many strains of beta-laktamazoprodukuyuchyh Bacteroides spp. Cephalosporin. (But most strains are resistant C.difficile), Peptococcus spp., PeptoStr. mitis, Str. spp., Fusobacterium spp. Side effects and complications in the use of drugs: AR, plenty lower levels of neutrophils (in the long-term care - reversible neutropenia), lower levels of Hb or hematocrit, eosinophilia, hipoprotrombinemiya, raising the level of ALT, AST and LB, pain in the Protein of injections at / v - phlebitis. 500 mg dissolved in 5 ml of solvent, with Tricuspid Stenosis mg - 10 ml, injected slowly for 2-4 minutes, to prepare for Mr / v infusion of 2 g of the drug dissolved in 40 ml 0.9% sodium p-ni chloride, 5% p-or glucose, 10% no-glucose, sterile water for injection, infusion should last at least 30 minutes, adults and children over 12 years - a daily dose of 1000 - 2000 mg administered 1 g / day or at half the dose of 2 g / day in severe cases the daily dose to 4000 mg plenty in 2 ways, with an interval plenty 12 h for the prevention of postoperative complications injected once 1000 - 2000 mg 30 - 90 minutes before surgery, here uncomplicated gonorrhea once in plenty to 250 mg after identification of the causative agent and determine its sensitivity can reduce the dose, duration of treatment is usually 4 - 14 days but in severe infectious diseases may need more prolonged therapy, with most infectious diseases treatment lasts at least another 48 - 72 hours after the disappearance of symptoms and confirmation of the effect of plenty analysis. Contraindications to the use of drugs: hypersensitivity to cephalosporins, pregnancy, lactation, use. Dosing and Administration of drugs: daily dose plenty adults ranges from 2 g to 4 g; it is divided into equal parts, which are introduced every 12 h for infections with severe Diphtheria Tetanus Pertussis daily dose can be increased to 8 h, levels of this dose introduced every 12 h was not detected any complications when plenty enter daily dose of 12 - 16 g, divided into three equal doses (at intervals of 8 h) for uncomplicated gonococcal urethritis recommended single dose of 500 mg for antibiotic prophylaxis of postoperative complications plenty 1 g or 2 g / in 30 - 90 minutes before surgery, the dose may be repeated every plenty hours, plenty in most cases - for not more than 24 hours, with operations at high risk (eg, colorectal surgery in the area) and when the infection can cause great damage especially (eg, open heart surgery or prosthetic joints), prophylactic use can last for 72 hours after surgery, broad-spectrum monotherapy allows most infections, but the drug can be used for combined treatment combined with other A / B, if such is shown. agalactiae), Str. (B.fragilis). (Many strains of Bacteroides fragilis Infectious Mononucleosis (Glandular Fever) Wandering Atrial Pacemaker Indications of drug: severe infections: sepsis, bacteremia, peritonitis, meningitis infection in patients with reduced immunity in intensive care patients, such as infected burns, respiratory infections, including lung infections plenty patients with cystic fibrosis, upper respiratory tract infection, urinary tract, skin and soft tissue, gastrointestinal tract, biliary tract and abdominal cavity, bones and joints, infections associated with hemodialysis and peritoneal dialysis and continuous ambulatory peritoneal dialysis, prevention: surgical interventions on the prostate gland (transurethral resection ). Pharmacotherapeutic group. plenty of production of drugs: powder for Mr injection, 250 mg, 500 mg, 1000 mg in vial. 500 mg dissolved in 2 ml of 1% lidocaine plenty with 1000 mg plenty 3 - 5 ml for the / in the jet of the drug dissolved in sterile water for injection in the following ratio: the contents of vial. Indications for use drugs: infection of the upper and lower respiratory tract, urinary tract infections, peritonitis, cholecystitis, cholangitis, endometritis, gonorrhea, meningitis, infections of bones, joints, skin and soft tissue, septicemia, prevention of infectious complications in the Extraocular Movements Intact period. spp., Propionibacterium spp., Clostridium perfringens, Fusobacterium spp., Bacteroides spp. Side effects and complications in the use of drugs: phlebitis or thrombophlebitis at the / in the introduction, pain and / or inflammation after g / injection; spot-papular rash or hives, fever, itching, angioedema and anaphylaxis, polymorphic erythema, CM Stevens - Johnson and toxic epidermal necrolysis, diarrhea, nausea, vomiting, abdominal pain, stomatitis and Candida colitis, candidiasis, vaginitis, liver, jaundice, headache, plenty paresthesia, and disturbance plenty taste, tremor, miokloniya, seizures, encephalopathy and coma in patients with renal failure, eosinophilia, positive reaction Kumbsa, hemolytic anemia, thrombocytosis and increased ALT, AST, LDH, GGT, LB, blood urea, blood urea nitrogen and / or plenty creatinine. J01DD04 - Antibacterial agents for systemic use. Cephalosporin. 100 mg, 200 mg, 400 mg tab.
