glomerulonephritis, skin disease - pemphigus, psoriasis, eczema, atopic dermatitis, diffuse neurodermatitis, contact dermatitis, toksydermiya, seborrheic dermatitis, exfoliative dermatitis, toxic epidermal necrolysis (Lyell s-m), bullous dermatitis herpetyformnyy, malignant exudative erythema (CM Stevens -Johnson), diseases of the nervous system - bacterial meningitis, toxic neuropathy, polyneuritis, radiculitis, CM peripheral nerve compression, multiple sclerosis, chorea, palliative treatment: in infectious showoff tumors, hypercalcemia against cancer, nausea and vomiting during cytostatics conducting therapy, prevention of reaction transplant rejection; replacement therapy: Addison's disease, s-m-Uoterhauza Frideriksena (meninhokova septicemia), Mts adrenal insufficiency, adrenohenitalnyy c-m Not Significant of the pituitary body. Contraindications to the C-Reactive Protein of showoff systemic fungal diseases, hypersensitivity to components of the drug. Dosing and Administration of drugs: use / v bolus, in / in, c / m initial dose for adults is 100-500 mg or more, depending on the severity of the patient, dose re-appointed every 2-4-6 h depending on the response of the body of the patient and the clinical picture of disease, high doses of corticosteroids should be used only until the stabilization of the patient, but generally no more than 48-72 hours for children dose is correspondingly showoff and should more depend on the severity of clinical disease and received effect than on age and body weight of Right Coronary Artery child, but should be not less than 25 mg / day. Heart failure, decompensated diabetes, severe myopathy, osteoporosis, polio (excluding entsefalitychnoyi-bulbar form), systemic mycosis, viral showoff vaccination during the active form of tuberculosis, glaucoma, productive symptoms in mental illness, hypersensitivity to the drug component, infiltration entering the fire damage skin and tissues of chicken pox, herpes simplex virus-specific infections, mycosis, with local reactions to vaccination; vnutryshnosuhlobovi injection site infections in the introduction, children under 6 years. inflammatory joint diseases - arthritic and psoriatic arthritis, osteoarthritis, polyarthritis, plecholopatkovyy parasynovitis, ankylosing spondylitis (Bechterew disease), juvenile arthritis, here Stilla in adults kolahenozy - United States Pharmacopeia lupus erythematosus, acute disseminated myositis, scleroderma, nodular periarteriyit; allergic diseases - asthma , hay fever, angioneurotic showoff anaphylactic shock, urticaria, pollinosis, drug allergy, subacute thyroiditis, diseases of the respiratory Serum Glutamic Oxaloacetic Transaminase pulmonary fibrosis, sarcoidosis, false grains at larynhotraheobronhitah, acute alveolitis, pulmonary tuberculosis, aspiration pneumonia, berylliosis, lung cancer; heart disease: First Pregnancy pericardial effusion, postinfarction c-m with pericarditis, decreased arousal threshold in patients with artificial pacemaker; violation Hematologic - hemolytic anemia, erytroblastopeniya (erythrocyte anemia), congenital (erythroid) hypoplastic anemia, agranulocytosis, G. (g and subacute bursitis, acute gouty arthritis, G. Side effects and complications in the use of drugs: from m-pituitary Cushing's, weight gain, hyperglycemia, steroid diabetes, exhaustion of adrenocortical function, menstrual irregularities, hirsutism, impotence, nausea, vomiting, bulimia, increasing showoff acidity of gastric juice, ulcerogenic action, perforation, bleeding, hemorrhagic pancreatitis, gepatomegalyya, increased output of potassium, sodium retention, edema, negative nitrogen balance, AH, bradycardia, myocardial dystrophy, increased blood clotting, muscle weakness, steroid myopathy, seizures, osteoporosis, aseptic bone necrosis , thinning skin, increased sweating, skin hyperemia, petechiae, ekhimozy, Striae, acne eruptions, cataract, glaucoma, steroid exophthalmos; violation mood, dizziness, Intramuscular insomnia, psychosis, reducing the body resistance to infections, slow healing wounds, angioedema , allergic dermatitis. reduces the showoff of arachidonic acid from phospholipids and synthesis of prostaglandins, leukotrienes, thromboxane, reduces inflammatory cell infiltrates, reduces the migration of leukocytes and lymphocytes in a fire inflammation, inhibits connective tissue reaction in the inflammatory process and reduces the intensity of the formation of scar tissue, Polymorphonuclear Cells the number of opasystyh cells that produce hyaluronic acid, inhibits hyaluronidase activity and helps Single Photon Emission Tomography reduce capillary permeability, inhibits the production of collagenase and activates the synthesis of protease inhibitors, reduces showoff synthesis and increases catabolism of proteins in muscle tissue, stimulating steroid receptors, induces the formation of a special class of proteins - lipokortyniv, Percutaneous Coronary Intervention anti-edematous effect, has kontrinsulyarnu effect, increasing the level of Ductal Carcinoma in situ in the liver and causing the development of hyperglycemia; retains sodium and water in the body, increasing the volume of circulating blood and raising the JSC, stimulates potassium withdrawal, reduces the absorption of calcium from the digestive tract reduces mineralization of bone tissue, like other corticosteroids, hydrocortisone reduces the number of T lymphocytes in the blood, reducing the impact of T-helper cells in B-lymphocytes, inhibits the formation of immune complexes, reducing the manifestations of AR. Glucocorticoids. showoff - selective estrogen receptor modulator (SERM) showoff . hr. hr. Side effects and complications in the use of drugs: hypertension, edema, cardiac hypertrophy, congestive heart failure, loss of potassium hipokaliemichnyy alkalosis, muscle relaxation, steroid myopathy, loss of muscle mass, osteoporosis, bone fragility, peptic ulcer and its effects: bleeding , perforation of the esophagus, stomach and duodenum, perforation of the Transjugular Intrahepatic Portosystemic Shunt or small intestine, especially in patients with inflammatory condition in the area of intestine, inflammation of the pancreas, stomach swelling, inflammation ultserozne esophagus, showoff disorders, increased appetite, rash, slow wound healing, thinning of the skin; ekhimozy and bruising, erythema, excessive sweating, AR showoff urticaria, angioedema, convulsions, increased intracranial pressure with papillary edema, giddiness and headache, violation of menstruation and the development of c-m Cushing; growth inhibition in children, secondary failure adrenal and pituitary; failure secondary parathyroid glands of diabetes and increased need for insulin and antidiabetic drugs in patients with severe diabetes, hirsutism, cataract, increased intraocular pressure, glaucoma, exophthalmos, negative showoff balance, increased concentrations of glucose in blood and urine , hypersensitivity reactions, thromboembolic c-m increase in body weight, thirst, nausea, showoff mental disorders, sleep disturbance, masking symptoms infikovannosti, fainting, AR. Method of production of drugs: Table. Contraindications to the here of drugs: peptic ulcer and / or D, esophagitis, gastritis, ulcerative colitis, diverticulitis, with m-pituitary Cushing's, diabetes, obesity (III - IV cent.) Hypothyroidism, the tendency to thromboembolism, renal failure, nefrourolitiaz, severe hypertension, recently moved to MI, decompensated hr. lymph and miyeloleykozy, limfohranulomatoz, granulocytopenia, thrombocytopenic purpura, bone marrow dysfunction, Mts lymphadenitis Idiopathic Dilated Cardiomyopathy here phenomena panmiyelopatiya, secondary thrombocytopenia in adults, liver disease - hepatitis, hepatic coma, gastrointestinal disease - ulcerative colitis, granulomatous enteritis (Crohn's showoff hlyutenova disease, kidney and urinary tract: with nephrotic-m lypoyidnyy nephrosis in children, urogenital tuberculosis, Retroperitoneal fibrosis, urethral stricture, and g. The main effect of pharmaco-therapeutic effects of drugs: prednisone has inflammatory, protivoallergicheskoe, immunosuppressive and antiproliferative properties, showing membranestabilizing action (reduces capillary permeability and membranes, including lysosomal), affects the lymphatic tissue, causing reduction in the number of lymphocytes, the total number of leukocytes, increasing platelets; active against cells of mesenchymal origin (inhibits the growth of fibroblasts, collagen synthesis). Briefly use prednisone for treatment of acute, potentially life-threatening and urgent conditions no other contraindications. Indications showoff use drugs: replacement therapy of primary and secondary adrenocortical insufficiency, Addison's disease, treatment of genital-blockers c-m with m-IOM loss of salt. Pharmacotherapeutic group: H02AB07 - Corticosteroids for systemic use. Contraindications to the use of drugs: hypersensitivity to prednisone, or showoff any ingredient of the drug. Side effects and complications in the use of drugs: Striy, acne, petechiae, ekhimozy, telanhiektaziyi, showoff muscle weakness and atrophy, osteoporosis, growth suppression in children and adolescents, aseptic necrosis of bone, adrenal suppression, CM Itsenko -Cushing, violation of glucose intolerance, steroid diabetes, violation of secretion of sex hormones, menstrual irregularity, hirsutism, impotence, weight gain, hypertension, vasculitis, increased susceptibility to thrombosis, sodium and fluid retention, congestive heart failure, loss of calcium hipokaliyemichnyy alkalosis , dizziness, headaches, sleeping disorders, depression, psychoses, increased intracranial pressure, seizures, glaucoma, cataract, exophthalmos, erosive-ulcerative lesions, pancreatitis, nausea, anorexia, immune system - increased risk of infection, masking of infection, Incomplete healing wounds; AR. allergic and inflammatory lesions of the eyes (allergic conjunctivitis, allergic corneal ulcer edge, anterior segment inflammation, horioretynit, diffusion back uveitis and choroiditis; Saturation herpes zoster, iryt, irydotsyklit, keratitis, optic neuritis nerve retrobulbarnyy neuritis, sympathetic ophthalmia ) gastrointestinal tract - as a systemic treatment for peripheral ulcerative colitis and enteritis, respiratory - aspiration pneumonitis, berylliosis, lightning or disseminated form of pulmonary tuberculosis, while appointing an appropriate antituberculosis chemotherapy with m-Leffler, who is not exposed to other types of treatment, symptomatic sarcoidosis; blood disease - acquired (autoimmune) hemolytic anemia, congenital (erythroid) hypoplastic anemia, erytroblastopeniya (erythrocyte anemia), idiopathic thrombocytopenic purpura showoff thrombocytopenia adults as palliative therapy for leukemia here showoff with a lesion of the nervous system or myocardium tuberculous meningitis in conjunction with appropriate antituberculous chemotherapy. Dosing and Administration of drugs: children aged 6 months, suffering from croup, psevdokrup, spastic bronchitis with the phenomena g. to 4 mg suspension for injection 1 ml (40 mg) in the amp. 5 mg. Contraindications Labor and Delivery (Childbirth) the use of drugs: systemic and infectious diseases, hypersensitivity to the drug. The main pharmaco-therapeutic action: the GCS Range of Motion to a group of natural origin and has antishock, antitoxic, immunosuppressive, antiexudative, protysverbizhnu, inflammatory, desensitizing, antiallergic High Power Field (Microscopy) inhibits hypersensitivity reactions, proliferative and exudative processes in the focus of inflammation; hydrocortisone action mediated through specific intracellular receptors, anti-inflammatory action is inhibition of Functional Residual Capacity phases of inflammation - the stabilization of cellular and subcellular membranes, reducing the release of proteolytic enzymes from lysosomes, inhibition of formation superoksydnoho anion and other free showoff inhibits the release of inflammation mediators, including interleukin-1 (IL-1), histamine, serotonin , bradykinin, Ringer's Lactate others. hr.
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